منابع مشابه
Maintaining genome integrity.
Introduction Genomes have always been vulnerable to damage from intraand extracellular sources such as oxidative species generated by cell metabolism, spontaneous base loss or modification, radiation and chemicals (Friedberg et al, 2005a). As a result, mechanisms to cope with DNA damage developed early in evolution and have been conserved. Organisms need some genome stability, but must allow mu...
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The Short stop (Shot/Kakapo) spectraplakin is a giant cytoskeletal protein, which exists in multiple isoforms with characteristics of both spectrin and plakin superfamilies. Previously characterized Shot isoforms are similar to spectrin and dystrophin, with an actin-binding domain followed by spectrin repeats. We describe a new large exon within the shot locus, which encodes a series of plakin ...
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Public Health Wales runs a successful brief intervention training programme. Over 3000 people have been trained to deliver alcohol brief interventions across Wales by the small (2 man) central Public Health Wales alcohol team. However, the team cannot keep up with demand from the 7 Welsh Health Boards to receive training. In order to address this, a train-the-trainers course has been developed,...
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There is a need for terminal management mechanisms for high volume embedded devices. Current technology provides mechanisms for adaptation of software on embedded devices during their deployment. These mechanisms give the opportunity to adapt a device to the wishes of the consumer at a specific location or time. While being useful to the user, these mechanisms might also jeopardize the software...
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Modern approaches to integrity monitoring suggest to generate triggers from constraints as part of database design and to utilize constraint simplification techniques for trigger optimization. Such proposals, however, have been restricted to static conditions which constrain single states only. In this paper, we show how to derive triggers from dynamic integrity constraints which describe prope...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2006
ISSN: 1469-221X,1469-3178
DOI: 10.1038/sj.embor.7400659